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RSS FeedsSensors, Vol. 14, Pages 6788-6796: Quorum Sensing Activity of Hafnia alvei Isolated from Packed Food (Sensors)

 
 

14 april 2014 09:49:02

 
Sensors, Vol. 14, Pages 6788-6796: Quorum Sensing Activity of Hafnia alvei Isolated from Packed Food (Sensors)
 


Quorum sensing (QS) is a mechanism adopted by bacteria to regulate expression of genes according to population density. N-acylhomoserine lactones (AHLs) are a type of QS signalling molecules commonly found in Gram-negative bacteria which have been reported to play a role in microbial spoilage of foods and pathogenesis. In this study, we isolated an AHL-producing Hafnia alvei strain (FB1) from spherical fish pastes. Analysis via high resolution triple quadrupole liquid chromatography/mass spectrometry (LC/MS) on extracts from the spent supernatant of H. alvei FB1 revealed the existence of two short chain AHLs: N-(3-oxohexanoyl) homoserine lactone (3-oxo-C6-HSL) and N-(3-oxo- octanoyl) homoserine lactone (3-oxo-C8-HSL). To our knowledge, this is the first report of the production of AHLs, especially 3-oxo-C8-HSL, by H. alvei.


 
201 viewsCategory: Chemistry, Physics
 
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