The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence (Molecular Cell)

In this issue of Molecular cell, Ivanova et al. report an in vivo function of the RNA m6A reader YTHDF2 in the regulation of the maternal transcriptome during oocyte maturation and its importance for the establishment of competent oocytes that can sustain early embryo development.