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RSS FeedsCSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue (Developmental Cell)

 
 

21 september 2017 18:18:00

 
CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue (Developmental Cell)
 


Bao et al. demonstrate an essential role for the arginine methyltransferase PRMT1 in epidermal progenitor maintenance. They further identify the kinase CSNK1a1 as a key PRMT1-interacting protein. CSNK1a1 phosphorylates PRMT1 and cooperates with PRMT1 to suppress GRHL3-mediated terminal differentiation.


 
145 viewsCategory: Cell Biology
 
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