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RSS FeedsEntropy, Vol. 19, Pages 629: Parametric PET Image Reconstruction via Regional Spatial Bases and Pharmacokinetic Time Activity Model (Entropy)

 
 

22 november 2017 15:17:45

 
Entropy, Vol. 19, Pages 629: Parametric PET Image Reconstruction via Regional Spatial Bases and Pharmacokinetic Time Activity Model (Entropy)
 


It is known that the process of reconstruction of a Positron Emission Tomography (PET) image from sinogram data is very sensitive to measurement noises; it is still an important research topic to reconstruct PET images with high signal-to-noise ratios. In this paper, we propose a new reconstruction method for a temporal series of PET images from a temporal series of sinogram data. In the proposed method, PET images are reconstructed by minimizing the Kullback-Leibler divergence between the observed sinogram data and sinogram data derived from a parametric model of PET images. The contributions of the proposition include the following: (1) regions of targets in images are explicitly expressed using a set of spatial bases in order to ignore the noises in the background; (2) a parametric time activity model of PET images is explicitly introduced as a constraint; and (3) an algorithm for solving the optimization problem is clearly described. To demonstrate the advantages of the proposed method, quantitative evaluations are performed using both synthetic and clinical data of human brains.


 
127 viewsCategory: Informatics, Physics
 
Entropy, Vol. 19, Pages 628: Design of Rate-Compatible Parallel Concatenated Punctured Polar Codes for IR-HARQ Transmission Schemes (Entropy)
Entropy, Vol. 19, Pages 635: Two-Party Zero-Error Function Computation with Asymmetric Priors (Entropy)
 
 
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