MyJournals Home  

RSS FeedsToxins, Vol. 9, Pages 379: Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa (Toxins)

 
 

23 november 2017 10:20:39

 
Toxins, Vol. 9, Pages 379: Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa (Toxins)
 


Cholera toxin B subunit (CTB) is a mucosal immunomodulatory protein that induces robust mucosal and systemic antibody responses. This well-known biological activity has been exploited in cholera prevention (as a component of DukoralŪ vaccine) and vaccine development for decades. On the other hand, several studies have investigated CTB`s immunotherapeutic potential in the treatment of inflammatory diseases such as Crohn`s disease and asthma. Furthermore, we recently found that a variant of CTB could induce colon epithelial wound healing in mouse colitis models. This review summarizes the possible mechanisms behind CTB`s anti-inflammatory activity and discuss how the protein could impact mucosal inflammatory disease treatment.


 
152 viewsCategory: Toxicology
 
Toxins, Vol. 9, Pages 378: A Supercluster of Neutralizing Epitopes at the Interface of Ricin`s Enzymatic (RTA) and Binding (RTB) Subunits (Toxins)
Toxins, Vol. 9, Pages 381: Interaction of Cholesterol with Perfringolysin O: What Have We Learned from Functional Analysis? (Toxins)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Toxicology


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten