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RSS FeedsMarine Drugs, Vol. 16, Pages 164: Structure of the Exopolysaccharide Secreted by a Marine Strain Vibrio alginolyticus (Marine Drugs)

 
 

20 may 2018 06:01:24

 
Marine Drugs, Vol. 16, Pages 164: Structure of the Exopolysaccharide Secreted by a Marine Strain Vibrio alginolyticus (Marine Drugs)
 


Vibrio alginolyticus (CNCM I-4151) secretes an exopolysaccharide whose carbohydrate backbone is decorated with amino acids, likely conferring its properties that are appreciated in cosmetics. Here, the secreted polysaccharide of another strain of V. alginolyticus (CNCM I-5034) was characterized by chromatography and one- and two-dimensional NMR spectroscopy experiments. The structure was resolved and shows that the carbohydrate backbone is made of four residues: D-galactose (Gal), D-galacturonic acid (GalA) D-N-acetylglucosamine (GlcNAc) and D-glucuronic acid (GlcA), forming a tetrasaccharide repetition unit [->4)-?-d-GlcA-(1->3)-?-d-Gal-(1->3)-?-d-GalA-(1->3)-?-GlcNAc(1->]. GlcA is derivatized with a lactate group giving `nosturonic acid`, and GalA is decorated with the amino acid alanine.


 
71 viewsCategory: Biochemistry, Molecular Biology, Pharmacology
 
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