MyJournals Home  

RSS FeedsToxins, Vol. 10, Pages 234: Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins (Toxins)

 
 

18 june 2018 12:00:36

 
Toxins, Vol. 10, Pages 234: Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins (Toxins)
 


Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis. Numerous pathogenic bacteria produce pore-forming toxins that break plasma membrane integrity and cause cell death by colloid-osmotic lysis. Eukaryotic cells, in turn, have developed different ways to cope with the effects of such membrane piercing. Here, we provide a short overview of the general mechanisms currently proposed for plasma membrane repair, focusing more specifically on the cellular responses to membrane permeabilization by pore-forming toxins and presenting new data on the effects and cellular responses to the permeabilization by an RTX (repeats in toxin) toxin, the adenylate cyclase toxin-hemolysin secreted by the whooping cough bacterium Bordetella pertussis, which we have studied in the laboratory.


 
63 viewsCategory: Toxicology
 
Toxins, Vol. 10, Pages 235: Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway Activation (Toxins)
Toxins, Vol. 10, Pages 233: Purification and Characterization of a Novel Insecticidal Toxin, ?-sparatoxin-Hv2, from the Venom of the Spider Heteropoda venatoria (Toxins)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Toxicology


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten