Parvalbumin-Interneuron Output Synapses Show Spike-Timing-Dependent Plasticity that Contributes to Auditory Map Remodeling (Neuron)

Vickers et al. study STDP at the inhibitory synapses formed by PV-interneurons in the auditory cortex. One limb of inhibitory STDP, developmentally gated GABAB-dependent iLTD, was identified as a candidate disinhibitory mechanism during auditory critical period plasticity.