Biochemistry
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17 august 2018 06:00:08 |
| Resurrecting the Bacterial Tyrosyl-tRNA Synthetase/tRNA Pair for Expanding the Genetic Code of Both E. coli and Eukaryotes (Cell Chemical Biology) |
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Tweet Italia et al. functionally replaced the native tyrosyl pair of E. coli with a heterologous counterpart to create ATMY strains, which can host the directed evolution of the `liberated` pair for selectively charging useful Uaas. The resulting engineered pairs can also be used for Uaa incorporation in eukaryotes. |
| 53 viewsCategory: Biology, Chemistry, Biochemistry |
 Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors (Cell Chemical Biology)The Bump-and-Hole Tactic: Expanding the Scope of Chemical Genetics (Cell Chemical Biology) 
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