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14 october 2018 06:02:04

 
Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody (Structure)
 




Antibodies targeting the tau protein can be used in immunotherapy or as diagnostic tools in Alzheimer disease. Zhang et al. report the biochemical, functional, and structural characterization of a human anti-tau antibody. Antibody CBTAU-24.1 recognizes a unique epitope in the proline-rich domain of tau and specifically detects pathological tau structures.


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37 viewsCategory: Biochemistry
 
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