MyJournals Home  

RSS FeedsTankyrase Mediates K63-Linked Ubiquitination of JNK to Confer Stress Tolerance and Influence Lifespan in Drosophila (Cell Reports)

 
 

16 october 2018 07:00:06

 
Tankyrase Mediates K63-Linked Ubiquitination of JNK to Confer Stress Tolerance and Influence Lifespan in Drosophila (Cell Reports)
 


Poly-ADP-ribosylation of Tnks substrates is closely coupled to the ubiquitin-proteasome pathway. Li et al. reveal that Tnks can induce K63-linked ubiquitination to enhance the kinase activity of JNK. This study uncovers the physiological functions of Tnks in lifespan, stress tolerance, and energy storage via positively regulating JNK signaling.


 
46 viewsCategory: Cell Biology
 
Theta Phase-Coordinated Memory Reactivation Reoccurs in a Slow-Oscillatory Rhythm during NREM Sleep (Cell Reports)
A Dimerization Function in the Intrinsically Disordered N-Terminal Region of Src (Cell Reports)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Cell Biology


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten