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16 october 2018 07:00:06

 
Critical Role for a Subset of Intestinal Macrophages in Shaping Gut Microbiota in Adult Zebrafish (Cell Reports)
 


Whether intestinal macrophages shape adult gut microbiota has not been demonstrated. Shiau et al. show that a severe loss of intestinal macrophages in adult zebrafish irf8 mutants can cause destabilization of gut commensal microbiota and a reduction of C1q expressions. Macrophage-specific rescue of irf8 mutants can reverse these effects.


 
55 viewsCategory: Cell Biology
 
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