Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration (Cell Reports)

Minegishi et al. use gene knockout, protein interaction assays, force microscopy, speckle imaging, and migration assays to analyze the molecular mechanics driving neuronal migration in vivo. Their data demonstrate that shootin1b mediates a mechanical clutch to produce force for the migration of olfactory interneurons in the brain.