Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast (Cell Reports)

Martín-García et al. show that fission yeast paxillin binds and recruits calcineurin (CN) phosphatase to the cytokinetic actomyosin ring (CAR). There, CN collaborates with Bgs1 in septum ingression and promotes the concentration of Pxl1 at the CAR in a feedback loop likely mediated through CN dephosphorylation of the Cdc15 F-BAR protein, essential for cytokinesis.