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RSS FeedsComplement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer`s Disease (Neuron)

 
 

10 november 2018 06:00:14

 
Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer`s Disease (Neuron)
 




Litvinchuk et al. show that complement C3aR plays a critical role in mediating immune homeostasis and tau pathology. The identification of a conserved C3aR network and crosstalk between complement signaling with STAT3 activation reveal novel pathogenic and therapeutic insights.


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56 viewsCategory: Neurology
 
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