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RSS FeedsSampling Native-like Structures of RNA-Protein Complexes through Rosetta Folding and Docking (Structure)

 
 

10 november 2018 15:00:23

 
Sampling Native-like Structures of RNA-Protein Complexes through Rosetta Folding and Docking (Structure)
 




RNA and protein molecules interact intimately during ribosome translation, pre-mRNA splicing, and other fundamental cellular processes. Structures of the relevant RNA-protein complexes often elude high-resolution determination. Kappel and Das report a computational Rosetta method RNP-denovo that can incorporate sparse experimental data and sample native-like structures of RNA-protein complexes.


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16 viewsCategory: Biochemistry
 
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