Oncology
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30 november 2018 23:00:03 |
| A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence (Cancer Cell) |
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Tweet Lu et al. show that MLL-rearranged leukemia is addicted to the transcription factor ZFP64 due to direct regulation of MLL by ZFP64. The MLL promoter has an unusually high number of ZFP64 binding motifs and is the most enriched location of ZFP64 occupancy in the human genome. |
| 90 viewsCategory: Cell Biology, Oncology |
 Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia (Cancer Cell)MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma (Cancer Cell International) 
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