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RSS FeedsIJMS, Vol. 19, Pages 3910: Melatonin May Increase Anticancer Potential of Pleiotropic Drugs (International Journal of Molecular Sciences)

 
 

8 december 2018 18:00:15

 
IJMS, Vol. 19, Pages 3910: Melatonin May Increase Anticancer Potential of Pleiotropic Drugs (International Journal of Molecular Sciences)
 




Melatonin (N-acetyl-5-methoxytryptamine) is not only a pineal hormone, but also an ubiquitary molecule present in plants and part of our diet. Numerous preclinical and some clinical reports pointed to its multiple beneficial effects including oncostatic properties, and as such, it has become one of the most aspiring goals in cancer prevention/therapy. A link between cancer and inflammation and/or metabolic disorders has been well established and the therapy of these conditions with so-called pleiotropic drugs, which include non-steroidal anti-inflammatory drugs, statins and peroral antidiabetics, modulates a cancer risk too. Adjuvant therapy with melatonin may improve the oncostatic potential of these drugs. Results from preclinical studies are limited though support this hypothesis, which, however, remains to be verified by further research.


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12 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 19, Pages 3912: Characterization and Expression Profiling of Neuropeptides and G-Protein-Coupled Receptors (GPCRs) for Neuropeptides in the Asian Citrus Psyllid, Diaphorina citri (Hemiptera: Psyllidae) (International Journal of Molecular Sciences)
IJMS, Vol. 19, Pages 3911: Circadian Rhythm Abnormalities in Parkinson`s Disease from Humans to Flies and Back (International Journal of Molecular Sciences)
 
 
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