The building industry is regarded a major contributor to climate change as energy consumption from buildings accounts for 40% of the total energy. The types of thermal comfort models used to predict the heating and cooling loads are critical to save energy in operative buildings and reduce greenhouse gas emissions (GHG). In this research, the internal air temperatures were recorded for over one year under the free floating mode with no heating or cooling, then the number of hours required for heating or cooling were calculated based on fixed sets of operative temperatures (18 °C–24 °C) and the adaptive thermal comfort model to estimate the number of hours per year required for cooling and heating to sustain the occupants’ thermal comfort for four full-scale housing test modules at the campus of the University of Newcastle, Australia. The adaptive thermal comfort model significantly reduced the time necessary for mechanical cooling and heating by more than half when compared with the constant thermostat setting used by the air-conditioning systems installed on the site. It was found that the air-conditioning system with operational temperature setups using the adaptive thermal comfort model at 80% acceptability limits required almost half the operating energy when compared with fixed sets of operating temperatures. This can be achieved by applying a broader range of acceptable temperature limits and using techniques that require minimal energy to sustain the occupants’ thermal comfort.