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RSS FeedsThe RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging (Molecular Cell)

 
 

13 january 2019 11:00:26

 
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging (Molecular Cell)
 




Aging leads to alterations in several key biological processes. However, whether and how these age-associated dysfunctions are interconnected is still poorly understood. Here, D`Amico et al. discovered that the RNA-binding protein PUM2 is induced upon aging and links impaired protein homeostasis and mitochondrial dysfunction, two well-known hallmarks of aging.


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59 viewsCategory: Molecular Biology, Cell Biology
 
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