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18 january 2019 10:01:55

 
Retromer Controls Planar Polarity Protein Levels and Asymmetric Localization at Intercellular Junctions (Current Biology)
 


Planar cell polarity--the organization of cells within a two-dimensional plane--is an important feature in tissue organization. Strutt et al. show that, in the Drosophila wing, endosomal recycling through retromer and its cargo adaptor Snx27 mediates the cell-surface localization of two key planar polarity proteins, Flamingo and Strabismus.


 
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