Biochemistry
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14 february 2019 21:00:10 |
| Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2 (Structure) |
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Tweet KIR3DL1 is an inhibitory receptor that regulates natural killer (NK) cell immune function. Cheng et al. describe NMR-based studies of its disordered cytoplasmic portion. The work characterized conformation dynamics as it binds with SH2 domains of the tyrosine phosphatase, SHP-2, which has broad implications in understanding inhibitory receptor function. |
| 75 viewsCategory: Biochemistry |
 Set7 Is a H3K37 Methyltransferase in Schizosaccharomyces pombe and Is Required for Proper Gametogenesis (Structure)Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1 (Structure) 
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