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RSS FeedsCell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos (Current Biology)

 
 

15 february 2019 02:01:43

 
Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos (Current Biology)
 


Chromosome segregation errors following fertilization lead to so-called mosaic-aneuploid embryos, which are thought to reduce the chance of a successful pregnancy. Here, Vázquez-Diez et al. provide evidence that the error-prone nature of those first few mitotic divisions may be attributable to an unusual weakness in the spindle assembly checkpoint.


 
88 viewsCategory: Biology
 
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