This paper presents the effectiveness of the interior search algorithm in economic power scheduling of a grid-tied DC microgrid with renewable generation (wind and photovoltaic) and battery energy storage. The study presents the modelling and simulation of various DC/DC converters for tracking maximum power from wind and photovoltaic sources and the bidirectional power flow of battery energy storage. The DC microgrid and its controllers were modelled and simulated in MATLAB/Simulink. The generating units were dispatched economically using the interior search algorithm with the objective to minimize the operating cost of the microgrid. The simulated results verify the effectiveness of the interior search algorithm as the daily cost of microgrid operation was reduced by 11.25%.