A Bidomain Model for Lens Microcirculation (Biophysical Journal)

There exists a large body of research on the lens of mammalian eye over the past several decades. The objective of the current work is to provide a link between the most recent computational models and some of the pioneering work in the 1970s and 80s. We introduce a general non-electro-neutral model to study the microcirculation in the lens of the eye. It describes the steady state relationships among ion fluxes, water flow and electric field inside cells, and in the narrow extracellular spaces between cells in the lens.