MyJournals Home  

RSS FeedsMST1 Negatively Regulates TNF?-Induced NF-?B Signaling through Modulating LUBAC Activity (Molecular Cell)

 
 

21 february 2019 20:03:45

 
MST1 Negatively Regulates TNF?-Induced NF-?B Signaling through Modulating LUBAC Activity (Molecular Cell)
 


Lee et al. identify MST1 as a component of TNF-RSC that phosphorylates HOIP at serine 1,066 and thereby inhibits the linear ubiquitin chain-forming activity of LUBAC in a TRAF2-dependent manner. MST1, by inhibiting an E3 ligase activity of HOIP, negatively regulates the NF-?B-dependent inflammatory gene expression induced by TNF?.


 
60 viewsCategory: Molecular Biology, Cell Biology
 
Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation (Molecular Cell)
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection (Molecular Cell)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Cell Biology


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten