The introduction of cool outdoor air can help in reducing the energy consumption for cooling during summer. Ventilative cooling potentials (VCPs) have been defined in various ways in the literature to represent potential cooling hours in specified outdoor temperature ranges. However, the energy-saving potential of ventilative cooling can differ between buildings in the same climatic zone depending on the buildings’ thermal characteristics and system operations. In this study, new VCPs are introduced with an index of temperature shift based on adaptive thermal comfort. This index can be determined based on the balance temperature difference of the buildings, which is defined as the heat gain in the building divided by the thermal transmission and air exchange characteristics of the building envelope under quasi-steady state conditions. The proposed method was also compared with those reported in the literature, including a computer-based VCP tool. It is the objective of the present study to investigate the correlation between VCPs and actual energy savings via ventilative cooling. Simulations were conducted in an office building for a four-month period during summer to calculate the energy saved via ventilative cooling in comparison with that achieved with a mechanical cooling system. Eight cities representing four different climatic conditions were considered: tropical, dry, temperate, and continental. Our results revealed a strong correlation between the energy savings and the proposed VCPs in the case of a proper temperature shift estimation in all climatic zones. The computerized VCP tool also exhibited good correlation with the calculated energy savings and with the VCPs proposed herein.