A method of estimating tropical cyclone (TC) intensity based on Haiyang-2A (HY-2A) scatterometer, and Special Sensor Microwave Imager and Sounder (SSMIS) observations over the northwestern Pacific Ocean is presented in this paper. Totally, 119 TCs from the 2012 to 2017 typhoon seasons were selected, based on satellite-observed data and China Meteorological Administration (CMA) TC best track data. We investigated the relationship among the TC maximum-sustained wind (MSW), the microwave brightness temperature (TB), and the sea surface wind speed (SSW). Then, a TC intensity estimation model was developed, based on a multivariate linear regression using the training data of 96 TCs. Finally, the proposed method was validated using testing data from 23 other TCs, and its root mean square error (RMSE), mean absolute error (MAE), and bias were 5.94 m/s, 4.62 m/s, and −0.43 m/s, respectively.