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RSS FeedsThe RIF1-PP1 Axis Controls Abscission Timing in Human Cells (Current Biology)

 
 

21 march 2019 16:02:06

 
The RIF1-PP1 Axis Controls Abscission Timing in Human Cells (Current Biology)
 


Bhowmick et al. have uncovered the mechanism by which the Aurora-B-kinase-driven abscission checkpoint is satisfied to allow cytokinesis in human cells. The DNA repair protein RIF1 localizes to and targets protein phosphatase 1 (PP1) to the midbody. PP1 then counteracts Aurora B to promote abscission.


 
47 viewsCategory: Biology
 
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