By using multiplatform satellite datasets, Argo observations and numerical model data, the upper ocean thermodynamic responses to Super Typhoon Soudelor are investigated with a focus on the impact of an ocean cyclonic eddy (CE). In addition to the significant surface cooling inside the CE region, an abnormally large rising in subsurface temperature is observed. The maximum warming and heat content change (HCC) reach up to 4.37 °C and 1.73 GJ/m2, respectively. Moreover, the HCC is an order of magnitude larger than that calculated from statistical analysis of Argo profile data in the previous study which only considered the effects caused by typhoons. Meanwhile, the subsurface warming outside the CE is merely 1.74 °C with HCC of 0.39 GJ/m2. Previous studies suggested that typhoon-induced vertical mixing is the primary factor causing subsurface warming but these studies ignored an important mechanism related to the horizontal advection caused by the rotation and movement of mesoscale eddies. This study documents that the eddy-induced horizontal advection has a great impact on the upper ocean responses to typhoons. Therefore, the influence of eddies should be considered when studying the responses of upper ocean to typhoons with pre-existing mesoscale eddies.