Cell Biology
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23 april 2019 18:00:18 |
| The Major Risk Factors for Alzheimer`s Disease: Age, Sex, and Genes Modulate the Microglia Response to A? Plaques (Cell Reports) |
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Tweet Sala Frigerio et al. show how microglia respond to amyloid-?, the Alzheimer`s disease (AD)-causing factor. Their major response, the ARMs response, is enriched for AD risk genes, is abolished by Apoe deletion, develops faster in female mice, and is also part of normal aging. Thus, major AD risk factors converge on microglia. |
| 64 viewsCategory: Cell Biology |
 Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages (Cell Reports)Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-?B Signaling Adaptation (Cell Reports) 
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