Contrasting Roles of Transcription Factors Spineless and EcR in the Highly Dynamic Chromatin Landscape of Butterfly Wing Metamorphosis (Cell Reports)

Using ATAC-seq, van der Burg et al. show that chromatin organization during butterfly wing development is highly dynamic. Motif enrichment analysis followed by ChIP-seq shows that DNA binding of transcription factor spineless, but not EcR, is strongly associated with opening chromatin.