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RSS FeedsDirect Lung Sampling Indicates That Established Pathogens Dominate Early Infections in Children with Cystic Fibrosis (Cell Reports)

 
 

23 april 2019 18:00:18

 
Direct Lung Sampling Indicates That Established Pathogens Dominate Early Infections in Children with Cystic Fibrosis (Cell Reports)
 


Jorth et al. studied lung lavages from CF children using sequence-based methods and extensive controls for upper airway and reagent contamination. The results argue against the CF infection pathogenesis hypothesis postulating that diverse communities of mostly oral bacteria inhabit lungs early in disease and suggest that differences in the samples` microbial diversity were driven by changes in the abundance of conventional CF pathogens against a fairly constant background of contaminants.


 
59 viewsCategory: Cell Biology
 
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