This article expands on knowledge about modeling tourism business. The basic scientific problem of the conducted research was the need to modernize the way of doing business in spa tourism enterprises by popularizing the business model and to provide an indication of the elements of the business model that should be grounded in the principles of sustainable spa development. The aim of the article is to present the results of our own research carried out in Polish spa enterprises in 2018. The key scientific issue was to examine the range of use of the business model templates in the management of tourism-treatment activities carried out in spas. Discussing the research results was preceded by a review of the literature on business models and the characteristics of activities carried out by spa tourism enterprises. The conducted research used qualitative methods, especially in-depth interviews, conducted with managers of the largest enterprises of spa tourism in Poland. Quantitative research was also conducted to examine the needs of tourists and patients. Our own scientific research has shown that spa enterprises in Poland very rarely and only within the scope limited to some elements of their activity, use the business model, and are not always aware of the wide range of its applications. As a result of the applications received, a business model dedicated to spa enterprises was developed. The article refers to the overtourism phenomenon in spas and indicates the need to put in business models, which are activities that protect spa areas against excessive pressure on tourism and the exploitation of natural resources.