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RSS FeedsNeuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration (Neuron)

 
 

17 june 2019 17:00:11

 
Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration (Neuron)
 




Hertz et al. identify the neuronally enriched protein RUFY3 as a key regulator downstream of (or in parallel to) caspase-3 in axon degeneration. RUFY3 is dephosphorylated and cleaved during degeneration. RUFY3 may provide a neuron-specific control point for neurons to locally control axon degeneration.


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38 viewsCategory: Neurology
 
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