The aim of this study was to develop a mathematical regression model for predicting end-use energy consumption in the residential sector. To this end, housing characteristics were collected through a field survey and in-depth interviews with residents of 71 households (15 apartment complexes) in Seoul, South Korea, and annual data on end-use energy consumption were collected from measurement systems installed within each apartment unit. Based on the data collected, correlativity between the field-survey data and end-use energy consumption was analyzed, and effective independent variables from the field-survey data were selected. Regression models were developed and validated for estimating six end uses of energy consumption: heating, cooling, domestic hot water (DHW), lighting, electric appliances, and cooking. Regression analysis for ventilation was not applied, and instead a calculation formula was derived, because the energy-consumption proportion was too low. The adj-R2 of the estimation model ranged from 0.406 to 0.703, and the maximum error between measured and estimated values was around ±30%, depending on the end use.