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RSS FeedsMolecules, Vol. 24, Pages 2268: A Novel Ratiometric Fluorescent Probe for Mercury (II) ions and Application in Bio-imaging (Molecules)

 
 

18 june 2019 16:00:31

 
Molecules, Vol. 24, Pages 2268: A Novel Ratiometric Fluorescent Probe for Mercury (II) ions and Application in Bio-imaging (Molecules)
 




Since the accumulation of mercury (II) ions in the environment and ecosystem causes serious problems to environment and disease, the recognition of Hg2+ ions and its bio-imaging is of high importance. In sight of the advantages of fluorescence probes, a new probe (PMH) was facilely synthesized by incorporating phenylimidazole fluorophore and 3-methyl-2- benzothiazolinone hydrazone hydrochloride monohydrate. The PMH probe exhibited a ratiometric response for Hg2+ ions with fluorescence intensity increasing at 520 nm and decreasing at 445 nm simultaneously. The PMH probe interacted with Hg2+ ions in seconds with high optical stability and showed good selectivity over other metal ions. In addition, the probe has excellent biocompatibility and imaging performance in cells and zebrafish.


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28 viewsCategory: Biochemistry, Chemistry, Molecular Biology
 
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