Experience shows that under unidirectional wind or certain terrain, the surface of post insulators is non-uniformly polluted between windward and leeward sides, which affects the flashover characteristics. In this paper, a formulation of residual pollution layer resistance was proposed under this non-uniformity and a typical post insulator was taken as an example to analyze and calculate its residual resistance. The theoretical resistance was verified by numerical simulations using COMSOL Multiphysics. The proposed resistance formulation was then implemented in a DC flashover dynamic model to determine the flashover voltage (Ucal), which was validated by artificial flashover tests. Then the factors affecting DC flashover voltage were analyzed. Research results indicate that: the residual resistance formulation agrees well with simulation results, especially when the arc length exceeds 70% of the leakage distance. The good concordance between theoretical and experimental flashover voltages with most relative error within ±10%, validates the flashover model and its residual resistance formulation. Ucal gets impaired under this non-uniformity. The degree of reduction is related to salt deposit density ratio (m) of windward to leeward side and leeward side area proportion (k).