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RSS FeedsAn Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis (Molecular Cell)

 
 

19 june 2019 23:02:33

 
An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis (Molecular Cell)
 


Mayank et al. describe a mechanism of crosstalk between the iron homeostasis and Fe-S cluster biogenesis pathways that is mediated by an interaction between the iron sensor FBXL5 and the CIA-targeting complex, which assembles cofactors on cytosolic proteins. This mechanism is required for the proper regulation of these pathways.


 
84 viewsCategory: Molecular Biology, Cell Biology
 
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