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RSS FeedsA Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability (Cell Host & Microbe)

 
 

20 june 2019 18:03:24

 
A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability (Cell Host & Microbe)
 


Wilke et al. describe an air-liquid interface (ALI) cultivation system that permits the efficient growth of C. parvum in vitro. ALI culture supports life cycle completion, thereby generating oocysts that can propagate in vitro, cause infection in mice, and enable in vitro genetic crosses, thus opening this system for future studies.


 
65 viewsCategory: Cell Biology, Immunology, Microbiology
 
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A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity (Cell Host & Microbe)
 
 
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