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RSS FeedsLINE-1 Evasion of Epigenetic Repression in Humans (Molecular Cell)

 
 

21 june 2019 08:00:44

 
LINE-1 Evasion of Epigenetic Repression in Humans (Molecular Cell)
 


Somatic genome mosaicism occurs in human neurons. Sanchez-Luque et al. show that a conserved YY1 binding site mediates methylation of young L1 retrotransposons. L1s lacking an intact YY1 site escape methylation in embryonic stem cells and can retrotranspose during hippocampal neurodevelopment.


 
93 viewsCategory: Molecular Biology, Cell Biology
 
Rearrangements within the U6 snRNA Core during the Transition between the Two Catalytic Steps of Splicing (Molecular Cell)
TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL (Molecular Cell)
 
 
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