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RSS FeedsA Role for FACT in RNA Polymerase II Promoter-Proximal Pausing (Cell Reports)

 
 

25 june 2019 18:00:27

 
A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing (Cell Reports)
 


FACT is a histone chaperone implicated in the assembly and disassembly of nucleosomes during transcription. Tettey et al. demonstrate that Drosophila FACT regulates patterns of the transcription-coupled histone marks H3K4me3 and H3K36me3 and helps to maintain promoter-proximal Pol II pausing.


 
42 viewsCategory: Cell Biology
 
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