Meta-Analysis Reveals Reproducible Gut Microbiome Alterations in Response to a High-Fat Diet (Cell Host & Microbe)

Bisanz and Upadhyay et al. execute a meta-analysis of previous studies evaluating the effect of a high-fat diet on the gut microbiome. They define reproducible features across studies for mechanistic experimentation and uncover that residual DNA contamination in experimental diets should be measured and accounted for in study design.