MyJournals Home  

RSS FeedsRegulation of Autophagic Flux by the 20S Proteasome (Cell Chemical Biology)

 
 

18 july 2019 20:03:09

 
Regulation of Autophagic Flux by the 20S Proteasome (Cell Chemical Biology)
 


Cells eliminate unwanted proteins through two major protein degradation systems called the proteasome and autophagy pathways. Njomen et al. found that the ubiquitin-independent 20S proteasome system is a key regulator of the autophagy pathway. Using a small-molecule activator of the 20S proteasome, the authors demonstrated that this new mechanism of crosstalk is achieved through 20S-mediated degradation of two key autophagy proteins, SNAP29 and STX17. These findings will likely open a new area of drug discovery research for protein-associated disorders.


 
155 viewsCategory: Biology, Chemistry, Biochemistry
 
Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth (Cell Chemical Biology)
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide (Cell Chemical Biology)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Biochemistry


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten