Reply to Bernhard Liedl, Klaus Goeschen, and Florian Wagenlehner`s Letter to the Editor re: Benoit Peyronnet, Emma Mironska, Christopher Chapple, et al. A Comprehensive Review of Overactive Bladder Pathophysiology: On the Way to Tailored Treatment. Eur Urol 2019, 75:988-1000 (European Urology)

We welcome the important comments raised by Liedl and colleagues and would like to thank them for their interest in our recently published manuscript [1]. This comprehensive review of overactive bladder (OAB) pathophysiology was meant to stimulate such discussions and to promote research in the field. We fully concur that the causative link between pelvic organ prolapse (POP) and OAB symptoms has been largely demonstrated [2]. From a broader perspective, we believe that OAB is a nonspecific symptom complex to which anything affecting the bladder can contribute to the pathogenesis, including lower urinary tract prolapse.