MyJournals Home  

RSS FeedsRNA homopolymers form higher-curvature virus-like particles than do normal-composition RNAs (Biophysical Journal)

 
 

17 august 2019 14:03:02

 
RNA homopolymers form higher-curvature virus-like particles than do normal-composition RNAs (Biophysical Journal)
 


Unlike double-stranded (ds)DNA, single-stranded (ss)RNA can be spontaneously packaged into spherical capsids by viral capsid protein because it is a more compact and flexible polymer. Many systematic investigations of this self-assembly process have been carried out using capsid protein from cowpea chlorotic mottle virus (CCMV), with a wide range of sequences and lengths of ssRNA. Among these studies are measurements of the relative packaging efficiencies of these RNAs into spherical capsids. In the present work we address a fundamental issue that has received very little attention, namely the question of the preferred curvature of the capsid formed around different RNA molecules.


 
256 viewsCategory: Biophysics
 
Probing the basis of ?-synuclein aggregation by comparing simulations to single-molecule experiments (Biophysical Journal)
Multi-scale Computational Modeling of Tubulin-Tubulin Lateral Interaction (Biophysical Journal)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Biophysics


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten