MyJournals Home  

RSS FeedsImpact of Graded Passive Cycling on Hemodynamics, Brain, and Heart Perfusion in Healthy Adults (Frontiers in Medicine)

 
 

20 august 2019 12:00:45

 
Impact of Graded Passive Cycling on Hemodynamics, Brain, and Heart Perfusion in Healthy Adults (Frontiers in Medicine)
 


Purpose: Passive in-bed cycling (PC) can provide the benefits of early mobilization to critically ill patients who are unable to exercise actively. However, the effect of PC on global hemodynamics and perfusion of ischemia-prone organs, such as the brain and the heart, is unknown. Therefore, prior to studying the effects of PC in hemodynamically fragile critically ill patients, we characterized hemodynamic, brain blood flow and cardiac function responses to a graded increase in PC cadence in a cohort of healthy subjects. Methods: We measured global hemodynamic indices, middle cerebral artery velocity (MCAv), and cardiac function in response to a graded increase in PC cadence. Using 5 minute stages, we increased cadence from 5 to 55 RPM in increments of 10 RPM, preceded and followed by 5 minute baseline and recovery periods at 0 RPM. The mean values obtained during the last 2 minutes of each stage were compared within and between subjects for all metrics using repeated measures ANOVA. Results: 11 healthy subjects (6 females) completed the protocol. Between subjects, there was no change in MCAv, cardiac function or hemodynamics with the graded increase in cadence with one exception. There was a 7% increase in mean arterial pressure from baseline to 55RPM, that persisted through the recovery period. Across subjects, responses were heterogeneous, with some experiencing reduction in cardiac index, cerebral blood flow and cardiac function, especially at higher cadence. Conclusions: In healthy adults, increasing PC cadence increased mean arterial pressure in all subjects, while cardiac index, cerebral blood flow and cardiac function responses varied between subjects. Application of PC to critically ill patients must therefore consider individual variation in responses and tailor the PC to the patient. It is essential to further characterize these responses to PC in the critically ill prior to wide-scale clinical implementation.


 
208 viewsCategory: Medicine
 
Biobanking for Viral Hepatitis Research (Frontiers in Medicine)
Dermoscopy of Melanoma and Non-melanoma Skin Cancers (Frontiers in Medicine)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Medicine


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten