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RSS FeedsRegulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG (Molecular Cell)

 
 

22 august 2019 11:00:12

 
Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG (Molecular Cell)
 




Zhou et al. show that the m6A reader protein hnRNPG interacts with m6A-modified nascent pre-mRNA and the phosphorylated C-terminal domain of RNA polymerase II to regulate alternative splicing. These interactions depend on an RGG region in the low-complexity region of hnRNPG.


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32 viewsCategory: Molecular Biology, Cell Biology
 
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