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RSS FeedsA VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge (Cell Reports)

 
 

17 september 2019 17:03:17

 
A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge (Cell Reports)
 




Woolsey et al. demonstrate that immune evasion functions of the Ebola virus VP35 protein are critical for virulence in non-human primates. A VP35 mutant Ebola virus does not cause lethal disease and instead elicits adaptive immune responses that can protect animals from wild-type Ebola virus challenge.


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15 viewsCategory: Cell Biology
 
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