MyJournals Home  

RSS FeedsSensors, Vol. 19, Pages 4022: Detection of Cu2+ Ions with GGH Peptide Realized with Si-Nanoribbon ISFET (Sensors)

 
 

18 september 2019 10:03:32

 
Sensors, Vol. 19, Pages 4022: Detection of Cu2+ Ions with GGH Peptide Realized with Si-Nanoribbon ISFET (Sensors)
 


The presence of heavy metal ions such as copper in the human body at certain concentrations and specific conditions can lead to the development of different diseases. The currently available analytical detection methods remain expensive, time-consuming, and often require sample pre-treatment. The development of specific and quantitative, easy-in-operation, and cost-effective devices, capable of monitoring the level of Cu2+ ions in environmental and physiological media, is necessary. We use silicon nanoribbon (SiNR) ion-sensitive field effect transistor (ISFET) devices modified with a Gly–Gly–His peptide for the detection of copper ions in a large concentration range. The specific binding of copper ions causes a conformational change of the ligand, and a deprotonation of secondary amine groups. By performing differential measurements, we gain a deeper insight into the details of the ion–ligand interaction. We highlight in particular the importance of considering non-specific interactions to explain the sensors’ response.


 
219 viewsCategory: Chemistry, Physics
 
Materials, Vol. 12, Pages 3023: Towards Optimization of Machining Performance and Sustainability Aspects when Turning AISI 1045 Steel under Different Cooling and Lubrication Strategies (Materials)
Sensors, Vol. 19, Pages 4020: Deceleration Planning Algorithm Based on Classified Multi-Layer Perceptron Models for Smart Regenerative Braking of EV in Diverse Deceleration Conditions (Sensors)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Physics


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten